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AuNPs induce cytotoxicity in rabbit articular chondrocytes. a cytotoxicity of 3, 13, and 45 nm AuNPs. *P < 0.05 and **P < 0.01, compared with control. b time-dependent cytotoxicity of 13 nm AuNPs. *P < 0.05 and **P < 0.01, compared with control. c Microscopic images of chondrocytes after treatment with 3, 13, and 45 nm AuNPs, respectively, for 24 h. Original magnification: ×200
