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13 nm AuNPs induce cytotoxicity independent of ROS. a FCM analysis on the ROS generation induced by 3, 13, and 45 nm AuNPs, respectively. b Statistical results from three independent FCM analyses. *P < 0.05 and **P < 0.01, compared with control. c Effect of NAC pretreatment on the cytotoxicity of 13 nm AuNPs
