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. 2016 Apr 28;12(6):746–756. doi: 10.7150/ijbs.13988

Figure 5.

Figure 5

Effect of LCP treatment on Galcetin-3 and EMT-related gene expression. Alteration of Galcetin-3 and EMT markers expression after different concentration of LCP treatment for 24 hrs in AGS cells (5A) and SW-480 cells (5B). The amount of protein was normalized by comparing the intensity of the α-tubulin band. 5C, In AGS and SW-480 xenograft nude mice experiment, when the tumor was measurable, mice were treated daily with 5-FU at 25 mg/kg by i.p. injection, or different dose of LCP by oral gavage, or by their combination, respectively. Results showed that 5.0% (wt/vol) LCP treatment significantly alters the expression of Galcetin-3, E-cadherin and Twist at mRNA level as compared with controls (all P<0.05). GAPDH was used as reference. All experiments represented the mean ± SD of triplicate independent experiments.