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. 2016 May 18;17:67. doi: 10.1186/s12863-016-0375-4

Fig. 5.

Fig. 5

The susceptibility of the mtDNA haplotypes to develop variants identified by next generation sequencing. a Total number of variants (mean ± SEM) for haplotypes A to E. b Susceptibility of the protein-coding regions to develop variants. c Susceptibility of non-protein-coding regions to develop variants. d Susceptibility of each electron transfer chain complex to develop variants. Data were analyzed using one-way and two-way ANOVA and Tukey’s multiple comparison test. *P < 0.05; **P < 0.01; ***P < 0.001; ****P < 0.0001