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. 2016 May 18;14:150. doi: 10.1186/s12957-016-0900-y

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© Li and Wang. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 3 — Effects of miR-452 on the biological behaviors of MG-63 cells. a qRT-PCR analysis confirmed increased miR-452 expression in MG-63 cells after miR-452 mimics transfection. **P < 0.01. b MTT assay showed that miR-452 reduced cell proliferation in vitro. **P < 0.01. c Flow cytometric analysis indicated that miR-452 promoted cell apoptosis. d Upregulation of miR-452 impeded cell invasion in MG-63 cells. **P < 0.01