Table 1.

Anthropometrics and Metabolic Data^a

	Whole Group	Nonobese	Obese
N	43	11	32
Age, y	38 ± 2	37 ± 3	39 ± 2
Weight, kg	106 ± 5	66 ± 3	120 ± 5b
BMI, kg/m2	38.7 ± 1.8	23.9 ± 0.7	44.0 ± 1.6b
Clamp, n	41	10	31
Fasting glucose, mmol/L	5.2 ± 0.1	5.2 ± 0.1	5.1 ± 0.1
Steady-state glucose, mmol/L	5.1 ± 0.1	5.2 ± 0.1	5.1 ± 0.1
Fasting insulin, pmol/L	89 [89]	44 [21]	104 [76]b
Steady-state insulin, pmol/L	736 [310]	576 [108]	811 [259]b
M, μmol · min−1 · kgffm−1	30 [24]	61 [31]	28 [19]b
M/I, μmol · min−1 · kgffm−1 · nM−1	45 [51]	103 [63]	33 [26]b
Mixed meal, n	37	10	27
Fasting glucose, mmol/L	5.1 ± 0.1	5.0 ± 0.1	5.1 ± 0.1
60-min glucose, mmol/L	6.9 ± 0.2	6.9 ± 0.5	6.9 ± 0.2
120-min glucose, mmol/L	6.3 ± 0.1	6.4 ± 0.2	6.2 ± 0.2
180-min glucose, mmol/L	6.0 ± 0.1	6.2 ± 0.3	5.9 ± 0.2
Fasting insulin, pmol/L	79 [56]	54 [30]	100 [73]b
60-min insulin, pmol/L	432 [304]	338 [196]	512 [391]c
120-min insulin, pmol/L	301 [342]	205 [134]	400 [552]d
180-min insulin, pmol/L	200 [283]	187 [141]	238 [324]
δInsulin AUC, nmol/L	209 [264]	169 [103]	276 [282]c

Abbreviation: δAUC, incremental area under the curve.

^aEntries are mean ± SEM or median [interquartile range].

^bP ≤ .0001 for the comparison of nonobese vs obese by Mann-Whitney test.

^cP ≤ .05.

^dP ≤ .01.