Figure 1.

Logistic regression: cross-sectional association of sex hormones and the presence of detectable CAC. In unadjusted or age-adjusted models, total circulating T concentrations exhibit a statistically significant negative association with CAC (first three CI values, left to right, respectively). After adjustment for conventional risk factors, however, T and CAC are nearly independent (final interval, with point estimate indistinguishable with the null value). Control for age and other factors induced similar effects for free T, E2, and E1.