Table 3.

Tobit Regression: Weighted Proportionate Difference in Calcification per Difference in Sex Steroid Levels, Scaled to Median Calcification Among Those With Detectable Calcium^a

	Age-Adjusted		Multivariable-Adjustedb
	% Difference (95% CI)	P Value	% Difference (95% CI)	P Value
CAC
Total T, 100 ng/dL	−23 (−41, −4)	.02	−0.8 (−20, 19)	.94
Free T, 10 ng/dL	−12 (−22, −2)	.02	−6 (−16, 4)	.25
SHBG, 10 nmol/L	−5 (−24, 13)	.58	12 (−7, 31)	.21
E1, pg/mL	2 (−1, 4)	.25	−0.7 (−4, 2)	.65
E2, pg/mL	−4 (−8, 1)	.09	−5 (−9, −1)	.01
AAC
Total T, 100 ng/dL	−21 (−36, −7)	.004	−0.4 (−15, 14)	.95
Free T, 10 ng/dL	−13 (−21, −5)	.002	−6 (−14, 2)	.13
SHBG, 10 nmol/L	−0.3 (−15, 14)	.97	13 (−1, 28)	.08
E1, pg/mL	4 (2, 6)	<.001	2 (−0.2, 4)	.09
E2, pg/mL	−0.3 (−4, 3)	.86	−0.6 (−4, 3)	.69
TAC
Total T, 100 ng/dL	−45 (−89, −0.8)	.046	−16 (−61, 29)	.47
Free T, 10 ng/dL	−25 (−53, 3)	.08	−12 (−39, 15)	.38
SHBG, 10 nmol/L	−11 (−53, 30)	.59	8 (−34, 50)	.70
E1, pg/mL	15 (9, 21)	<.001	11 (5, 17)	<.001
E2, pg/mL	−3 (−14, 7)	.55	0.2 (−9, 10)	.96

^aSee Table 2.

^bAdjusted for age, BMI, T2DM, HDL-cholesterol, total cholesterol, triglycerides, smoking, diastolic blood pressure, and prevalent cardiovascular disease.