Table 1.
Baseline Characteristics of Lean and Obese Study Subjects
| Control Group (n = 62) | Obese Group (n = 59) | P Value | |
|---|---|---|---|
| Sex, female n (%) | 41 (66) | 48 (81) | |
| Age (y) | 37 (22–64) | 41.4 (23–66) | .03 |
| BMI (kg/m2) | 22.1 (17.6–26) | 45.2 (35.6–68.6) | <.0001 |
| AST (IU/liter) | 19.6 (12–47) | 18.6 (7–43) | .46 |
| ALT (IU/liter) | 16.2 (8–42) | 24.4 (7–81) | <.0001 |
| Total cholesterol (mg/dL) | 175.5 (120–258) | 174.7 (112–239) | .87 |
| Triglycerides (mg/dL) | 72.7 (34–165) | 150.3 (40–651) | <.0001 |
| HDL cholesterol (mg/dL) | 67.2 (30–97) | 45.5 (24–78) | <.0001 |
| LDL cholesterol (mg/dL) | 92.2 (16–151) | 100.2 (38–151) | .11 |
| Glucose (mg/dL) | 76.8 (56–106) | 110.2 (75–259) | <.0001 |
| Insulin (uU/mL) | 2.9 (0.1–13.0) | 7.5 (0.4–19.6) | <.0001 |
| HOMA-IR | 0.57 (0.02–3.18) | 1.99 (0.1–5.0) | <.0001 |
| HbA1c (%) | 5.2 (4.5–5.8) | 6.3 (4.7–10.4) | <.0001 |
| Adiponectin (ng/ml) | 15 936 (4622–37 197) | 7415 (3214–17 304) | <.0001 |
| CTRP9 (ng/ml) | 76.5 (22.4–120.5) | 115.3 (60.9–254.5) | <.0001 |
| Leptin (pg/ml) | 10 034 (658–52 585) | 59 156 (1825–163 543) | <.0001 |
Data are means, with range. P values calculated by two-tailed t test. Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase.