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. 2016 Mar 3;157(5):2015–2027. doi: 10.1210/en.2015-1740

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Figure 6. — Serum LH (A) and FSH (B) in Blank-SAP and NK₃-SAP rats receiving an E₂P regimen to induce an LH surge in the afternoon (mean ± SEM). The level of LH during the surge was 3-fold higher in KNDy-ablated rats relative to controls. The FSH surge was also higher in KNDy-ablated rats. The am blood sample was taken at 8:30 am, and the pm blood sample was taken between 3:30 and 4:30 pm. n = 7 Blank-SAP and n = 4 NK₃-SAP rats. +, significantly different, Blank-SAP vs NK₃-SAP, P < .001; #, significantly different, Blank-SAP vs NK₃-SAP, P < .01; *, significantly different than am, within NK₃-SAP, P < .001.