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. 2016 Mar 4;157(5):1839–1851. doi: 10.1210/en.2015-1768

Figure 8.

Figure 8.

Oral JTE-013 administration reduces body/epididymal fat tissue and improves glucose tolerance and insulin sensitivity in ob/ob mice. A, Ten-week-old WT and ob/ob mice were fed a normal diet powder containing JTE-013 for 4 weeks. A, Body weight changes after the diet change. B, ip-GTT. C, ip-ITT. In B and C, the AUCs are shown as inset graphs. D, Epididymal fat weights after 4 weeks. E, Average diameters of 300 epididymal adipocytes. Data are mean ± SEM (n, sample numbers); *, P < .05; **, P < .01; ***, P < .01 vs no JTE-013 samples (t test).