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Circulating metabolic peptides. A, Circulating levels of insulin at 4.5, 8.5, and 12.5 months of age in iC-GHRKO (n = 8) and control (n = 24) littermates. Circulating levels of C-peptide (B), leptin (C), MCP-1 (D), IL-6 (E), and resistin (F) in 12.5-month-old iC-GHRKO (n = 8) and control (n = 24) littermates are shown. *, Significant difference between genotypes (P < .05).
