Figure 2.

Illustration of the tools employed to evaluate neurological severity score (NSS) and an example of task assessment.

(A) “Beam walk”. To fulfill the task a mouse should cross the beam (3, 2, 1 cm) into opposite side; (B) “Exit circle”. A healthy mouse should find the exit out of circle within 3 minutes. (C) An example of “Beam walk” test; (D) “Round stick balance”. The task is considered successful if a mouse is able to balance with all four paws during 10 seconds.