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. 2016 Apr;11(4):636–640. doi: 10.4103/1673-5374.180750

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Copyright: © Neural Regeneration Research

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 3.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.

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Effect of lipoxin A4 (LXA4) on neurological deficits and brain infarct volume in diabetic rats with cerebral ischemia/reperfusion (I/R) injury.

(A) Neurological scores. The higher the score, the worse the neurological function. (B) Representative 2,3,5-triphenyltetrazolium chloride-stained brain sections (infarcted areas are white). Rats were subjected to 2 hours of middle cerebral artery occlusion followed by 24 hours of reperfusion. (C) Brain infarct volume. Data are expressed as the mean ± SEM (n = 6 rats per group). The data of different groups were compared by one-way analysis of variance (ANOVA) followed by Student-Newman-Keuls tests (for normally distributed data). *P < 0.05, vs. I/R. S: Sham group; I/R: diabetes mellitus + I/R injury group; LXA4: diabetes mellitus + I/R injury + LXA4 group.