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. Author manuscript; available in PMC: 2016 May 18.

Published in final edited form as: Int Forum Allergy Rhinol. 2015 Dec 3;6(2):178–184. doi: 10.1002/alr.21638

A: Ethanol stimulation vs. total stimulation [ethanol+ forskolin (0.5%)] of transepithelial Cl⁻ conductance (n = 9 per condition) indicates ethanol concentrations > 0.5% result in decreased total stimulation.

B: Ethanol (0.5%) significantly increased Cl⁻ transport when compared to PBS control (n = 9; p<0.05). Total stimulated ΔI_SC following application of [ethanol (0.05%) + forskolin] were statistically different from those with [PBS + forskolin] (total stimulated ΔI_SC of ethanol + forskolin (n = 9) = 20.7 ± 1.2 μA/cm²; total stimulated ΔI_SC of PBS + forskolin (n = 4) = 13.0 ± 0.5 μA/cm², p = 0.002). * Statistical significance (p < 0.05)

A: Ethanol stimulation vs. total stimulation [ethanol+ forskolin (0.5%)] of transepithelial Cl⁻ conductance (n = 9 per condition) indicates ethanol concentrations > 0.5% result in decreased total stimulation.

B: Ethanol (0.5%) significantly increased Cl⁻ transport when compared to PBS control (n = 9; p<0.05). Total stimulated ΔI_SC following application of [ethanol (0.05%) + forskolin] were statistically different from those with [PBS + forskolin] (total stimulated ΔI_SC of ethanol + forskolin (n = 9) = 20.7 ± 1.2 μA/cm²; total stimulated ΔI_SC of PBS + forskolin (n = 4) = 13.0 ± 0.5 μA/cm², p = 0.002). * Statistical significance (p < 0.05)