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. Author manuscript; available in PMC: 2016 May 18.
Published in final edited form as: Mol Cell. 2014 Dec 31;57(2):376–388. doi: 10.1016/j.molcel.2014.12.004

Figure 5. The Landscape of Protein-Bound RNA Motifs.

Figure 5

(A–E) Overrepresented sequence motifs identified by MEME (A) or HOMER (B–E) analysis of PPS sequences.

(F–J) The relative distribution of protein-bound and unbound motifs from (A) to (E) throughout specific pre-mRNA regions, including the CDS (blue), 5′ UTR (purple), 3′ UTR (green), and intron (orange).

(K–O) Structure score profiles at RBP-binding motifs from (A) to (E). Average structure score at each position ± 50 nt up- and downstream of bound (red lines) and unbound (orange lines) motif occurrences from (A) to (E).