Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2015 Apr 17;22(3):313–322. doi: 10.1177/1073858415581986

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2015

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

PMC Copyright notice

Figure 1. — Deep brain stimulation (DBS) inhibits local neuronal firings. (A) Responses of an internal pallidal (GPi) neuron to local repetitive high-frequency stimulation (GPi-DBS; 30 µA, 100 Hz, 10 pulses; arrows) in a normal monkey. Raw traces of spike discharges after removing the stimulus artifacts (1) and raster and peristimulus time histograms (PSTHs; 100 trials; binwidth, 1 ms) (2) are shown. Spontaneous discharge of the GPi neuron was completely inhibited by GPi-DBS. (B) Effect of local injection of gabazine (GABA_A receptor antagonist) in the vicinity of the recorded GPi neuron. The inhibition induced by GPi-DBS (1) was abolished after gabazine injection (2). Modified from Chiken and Nambu (2013).