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. 2015 Apr 17;22(3):313–322. doi: 10.1177/1073858415581986

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© The Author(s) 2015

This article is distributed under the terms of the Creative Commons Attribution-NonCommercial 3.0 License (http://www.creativecommons.org/licenses/by-nc/3.0/) which permits non-commercial use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access page (https://us.sagepub.com/en-us/nam/open-access-at-sage).

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Figure 2. — Directly evoked spikes of internal pallidal (GPi) neurons are inhibited during GPi–deep brain stimulation (DBS). (A) Raw traces showing directly evoked spikes (arrowheads) of a GPi neuron by GPi-DBS (40 µA, 100 Hz, 10 pulses; arrows with dotted lines) in a normal monkey. Traces with long (top) and short (bottom) time scales are shown. GPi-DBS failed to evoke spikes (from 6th to 10th stimuli). (B) Effects of local gabazine injection on the inhibition of directly evoked GPi responses. Gabazine injection decreased the failure rate, and each stimulus successfully evoked spikes (5th, 9th, and 10th stimuli). Modified from Chiken and Nambu (2013).