Table 5.

Serious mental illness characteristics associated with beta blocker and ACEI/ARB prescribing among patients with coronary heart disease and heart failure

	Beta blockers if recorded with CHD or HF (n = 3347)				ACEI/ARB if recorded with CHD or HF (n = 3760)
	n (%)	Unadjusted OR (95% CI)	Adjusted for sociodemographics ORa (95% CI)	Additionally adjusted for consultation rate ORb(95% CI)	n (%)	Unadjusted OR (95% CI)	Adjusted for sociodemographics ORa (95% CI)	Additionally adjusted for consultation rate ORb (95% CI)
Non-SMI	3279 (68.3)	1.00	1.00	1.00	3677 (76.6)	1.00	1.00	1.00
SMI overall	68 (52.7)	0.52 (0.36 to 0.73)e	0.50 (0.35 to 0.73)e	0.48 (0.33 to 0.69)e	83 (64.3)	0.55 (0.38 to 0.79)e	0.49 (0.34 to 0.73)e	0.42 (0.28 to 0.62)e
SMI by diagnosis
Schizophrenia	30 (50.0)	0.46 (0.28 to 0.77)d	0.42 (0.24 to 0.73)d	0.38 (0.22 to 0.67)e	36 (60.0)	0.46 (0.27 to 0.77)d	0.35 (0.20 to 0.60)e	0.27 (0.15 to 0.48)e
Bipolar affective disorder	8 (40.0)	0.31 (0.13 to 0.76)c	0.37 (0.15 to 0.94)c	0.35 (0.14 to 0.90)c	11 (55.0)	0.37 (0.15 to 0.90)c	0.49 (0.18 to 1.26)	0.41 (0.16 to 1.09)
Other non-organic psychoses	8 (61.5)	0.74 (0.24 to 2.27)	0.78 (0.25 to 2.42)	0.75 (0.24 to 2.33)	12 (92.3)	3.66 (0.48 to 28.2)	3.81 (0.49 to 29.4)	3.44 (0.44 to 26.7)
Depot injectable
No	42 (56.8)	0.61 (0.38 to 0.97)c	0.58 (0.36 to 0.96)c	0.56 (0.34 to 0.92)c	48 (64.9)	0.56 (0.35 to 0.91)c	0.49 (0.29 to 0.81)d	0.43 (0.26 to 0.72)e
Yes	11 (36.7)	0.27 (0.13 to 0.57)e	0.26 (0.12 to 0.60)d	0.22 (0.09 to 0.52)e	18 (60.0)	0.46 (0.22 to 0.95)c	0.41 (0.18 to 0.91)c	0.32 (0.14 to 0.72)d
Typical antipsychotic
No	28 (50.9)	0.48 (0.28 to 0.82)d	0.50 (0.28 to 0.89)c	0.49 (0.27 to 0.86)c	34 (61.8)	0.49 (0.29 to 0.85)c	0.42 (0.23 to 0.75)d	0.37 (0.21 to 0.67)e
Yes	25 (51.0)	0.48 (0.27 to 0.85)c	0.44 (0.24 to 0.81)d	0.39 (0.21 to 0.73)d	32 (65.3)	0.57 (0.32 to 1.03)	0.52 (0.28 to 0.97)c	0.42 (0.22 to 0.80)d
Atypical antipsychotic
No	8 (87.1)	0.62 (0.21 to 1.78)	0.59 (0.20 to 1.71)	0.54 (0.18 to 1.58)	8 (57.1)	0.41 (0.14 to 1.18)	0.41 (0.14 to 1.20)	0.32 (0.10 to 0.96)c
Yes	45 (50.0)	0.46 (0.31 to 0.70)e	0.45 (0.29 to 0.71)e	0.43 (0.27 to 0.67)e	58 (64.4)	0.55 (0.36 to 0.86)d	0.47 (0.30 to 0.76)d	0.41 (0.26 to 0.66)e
Any indicator of severityf
No	45 (57.0)	0.61 (0.39 to 0.96)c	0.56 (0.35 to 0.91)c	0.54 (0.33 to 0.87)c	56 (70.9)	0.74 (0.46 to 1.21)	0.61 (0.37 to 1.01)	0.52 (0.31 to 0.87)c
Yes	23 (46.0)	0.39 (0.23 to 0.69)e	0.43 (0.24 to 0.77)d	0.39 (0.21 to 0.71)d	27 (54.0)	0.36 (0.20 to 0.63)e	0.37 (0.20 to 0.66)e	0.31 (0.17 to 0.56)e
Any indicator of riskg
No	54 (59.3)	0.68 (0.44 to 1.03)	0.64 (0.41 to 1.00)	0.61 (0.39 to 0.96)c	64 (70.3)	0.72 (0.46 to 1.14)	0.65 (0.40 to 1.04)	0.56 (0.35 to 0.91)c
Yes	14 (36.8)	0.27 (0.14 to 0.52)e	0.28 (0.14 to 0.57)e	0.25 (0.12 to 0.51)e	19 (50.0)	0.31 (0.16 to 0.58)e	0.27 (0.14 to 0.54)e	0.22 (0.11 to 0.44)e

ACEI/ARB = angiotensin-converter enzyme inhibitor/angiotensin receptor blocker. CHD = coronary heart disease. HF = heart failure. OR = odds ratio. SMI = severe mental illness.

^aAdjusted for age (continuous), sex, ethnic group, borough-level deprivation, and recorded CHD/HF.

^bAdditionally adjusted for mean annual number of primary consultations.

^cP <0.05.

^dP <0.01.

^eP <0.001.

^fIncludes any of: ever had an inpatient stay, any record of being treated under the Mental Health Act, any record of difficulty managing their physical health, or any record of an Assertive Outreach/Crisis/A&E episode.

^gIncludes any of: recorded history of violence, recorded history of non-compliance, and any record of a forensic history.