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. 2016 May 18;11(5):e0155799. doi: 10.1371/journal.pone.0155799

Fig 2. GGA3KO mice do not exhibit deficits in spatial reference memory.

Fig 2

GGA3KO and GGA3WT were subjected to Morris Water Maze test. Both groups of mice demonstrate a significant decrease in latency to find the hidden platform (8 trials/day; 25min ITI) in initial testing (Days 1–3) phase (A) and during reversal phase (Days 8–10) (B) (Days 1–3 ***p value <0.001, Days 8–10 ***p value <0.001) however no significant difference in latency is observed between GGA3KO and WT mice on any day of testing. No significant differences were observed in the number of platform crossings during the 1st or 2nd probe trial (C-D). The graphs represent mean ± SEM. n = 14 GGA3KO mice and n = 14 GGA3WT mice of mixed gender. Two-way ANOVA repeated measures and t-test were used for latency to platform and probe trials, respectively.