Fig 4. Effect of maternal environment and offspring diet on mesenteric resistance artery responses to phenylephrine and sodium nitroprusside (SNP).

All blood vessels were obtained from adult (31 week-old) wild type (WT) male offspring of WT-control or Lepr^db/+ (db/+) dams. (A-D) Phenylephrine-induced vasoconstriction responses. (E-H) SNP-induced vasodilatory responses. Data are means ± SEM of n = 5–7 number of animals (vessels) per treatment group combination. SD, standard diet; HFD, high fat diet.