Figure 2.
CaeA leads to survivin up-regulation. HEK293 cells stably expressing GFP or GFP-CaeA were exposed to UV-light (200 J/m2 or 800 J/m2) and incubated for 6 h. (a) Proteins were separated by SDS-PAGE, transferred to a PVDF membrane and probed with antibodies against survivin, XIAP and actin as loading control. The result of one representative experiment out of 3 independent experiments with similar results is shown. (b) Densitometric analysis of the survivin/actin ratio was performed using ImageJ. The data shown represent average values ± SD from at least 3 independent experiments. *P < 0.05 ***P < 0.001