Table 2.

suggested dosages of the most common antimicrobials used for the treatment of BSIs in critically ill patients.

Antimicrobial	Dose
Ceftazidime	15 mg/kg loading dose, then 6-8 g every 24 h c.i.
Cefepime	15 mg/kg loading dose, then 2 g every 8 h c.i.
Piperacillin/tazobactam	4.5 g (loading dose), then 18 g every 24 h c.i.
Meropenem	1-2 g every 8 h e.i.
Ertapenem	1 g every 12 h
Amikacin	25-30 mg/kg every 24 h
Gentamicin	7 mg/kg every 24 h
Vancomycin	1 g loading dose, then 30 mg/kg every 24 h c.i.
Daptomycin	8-10 mg/kg every 24 h
Tigecycline	100-200 mg (loading dose), then 50-100 mg every 12 h
Colistin	9 MU loading dose, 4.5 MU every 12 h
RifampinFosfomycin	600-900 mg every 24 h4-6 g every 6 h c.i.
Caspofungin	70 mg, then 50 mg every 24 h
Anidulafungin	200 mg, then 100 mg every 24 h
Micafungin	100 mg every 24 h

Notes. c.i.: continuous infusion

e.i: extended infusion (6-8 hours)