Table 1. Characteristics of 1,316 older patients with non-metastatic rectal cancer receiving preoperative treatment and surgical resection by postoperative treatment type, 2004-2009.
Characteristics | No postoperative chemotherapy | Postoperative 5-FU/ capecitabine alone | Postoperative oxaliplatin | |||
---|---|---|---|---|---|---|
n=666 | % | n=309 | % | n=341 | % | |
Age at diagnosis | ||||||
66-69 years | 129 | 19 | 85 | 28 | 141 | 41 |
70-74 years | 213 | 32 | 98 | 32 | 113 | 33 |
75-79 years | 177 | 27 | 73 | 24 | 74 | 22 |
80+ years | 147 | 22 | 53 | 17 | 13 | 4 |
Male | 381 | 57 | 178 | 58 | 214 | 63 |
Race/ethnicity | ||||||
White, Non-Hispanic | 526 | 79 | 244 | 79 | 287 | 84 |
Black, Non-Hispanic | 43 | 6 | 16 | 5 | 14 | 4 |
Other, Non-Hispanic | 46 | 7 | 23 | 7 | 23 | 7 |
Hispanic | 51 | 8 | 26 | 8 | 17 | 5 |
Marital status | ||||||
Married | 385 | 58 | 196 | 63 | 220 | 65 |
Widowed | 173 | 26 | 62 | 20 | 61 | 18 |
Single | 58 | 9 | 23 | 7 | 30 | 9 |
Separated or Divorced | 50 | 8 | 28 | 9 | 30 | 9 |
Metropolitan residence | 598 | 90 | 257 | 83 | 309 | 91 |
% living below poverty line (census tract) | ||||||
Quartile 1 (low) | 151 | 23 | 65 | 21 | 107 | 31 |
Quartile 2 | 168 | 25 | 71 | 23 | 90 | 26 |
Quartile 3 | 173 | 26 | 82 | 27 | 76 | 22 |
Quartile 4 (high) | 174 | 26 | 91 | 29 | 68 | 20 |
AJCC pathologic stage | ||||||
0 and I | 204 | 31 | 75 | 24 | 54 | 16 |
II | 298 | 45 | 121 | 39 | 120 | 35 |
III | 164 | 25 | 113 | 37 | 167 | 49 |
Diagnosis year | ||||||
2004 | 112 | 17 | 62 | 20 | 26 | 8 |
2005 | 125 | 19 | 61 | 20 | 62 | 18 |
2006 | 110 | 17 | 46 | 15 | 60 | 18 |
2007 | 118 | 18 | 46 | 15 | 64 | 19 |
2008 | 91 | 14 | 43 | 14 | 77 | 23 |
2009 | 110 | 17 | 51 | 17 | 52 | 15 |
Rectum vs. Rectosigmoid | 597 | 90 | 278 | 90 | 309 | 91 |
Preoperative chemoradiation vs. radiation therapy only | 527 | 79 | 290 | 94 | 312 | 91 |
Selected comorbidities | ||||||
Congestive heart failure | 43 | 6 | 14 | 5 | NR | NR |
COPD | 65 | 10 | 23 | 7 | 26 | 8 |
Diabetes without sequelae | 141 | 21 | 72 | 23 | 60 | 18 |
Diabetes with sequelae | 19 | 3 | 11 | 4 | 13 | 4 |
30-day post-operative hospitalization | 245 | 37 | 69 | 22 | 58 | 17 |
Predicted probability of ADL-D (median, IQR) | 0.034 (0.023, 0.054) | 0.031 (0.021, 0.046) | 0.026 (0.020, 0.038) |
Abbreviations: 5-FU=5-fluorouracil; NR=not reportable due to cell size less than 11, AJCC=American Joint Commission on Cancer, COPD=chronic obstructive pulmonary disease, ADL-D=activities of daily living dependence.