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. Author manuscript; available in PMC: 2017 Jan 20.
Published in final edited form as: Neuron. 2016 Jan 20;89(2):325–336. doi: 10.1016/j.neuron.2015.12.024

Figure 3. Loss of ZIG-10 increases synapse density.

Figure 3

(A) Representative confocal images of immunostaining for the active zone protein UNC-10 in the dorsal cord. Brackets mark UNC-10 negative gaps greater than 2 µm. (B) zig-10(0) displayed an increased number of synapses. (C) zig-10(0) showed a reduced number of UNC-10 negative gaps between synapses. (D–E) zig-10(0) had a normal active zone area and did not alter UNC-10 staining intensity as measured in arbitrary units (a. u.). (F) zig-10(0) increased the number of synapses in acr-2(gf) background.

The data in B-F are represented as mean ± SEM. ns=not significant, *p<0.05, **p≤0.01, ***p≤0.001, and ****p≤0.0001. Sample size is shown within each bar. See also Figure S3.