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. Author manuscript; available in PMC: 2016 May 31.
Published in final edited form as: Cell Rep. 2016 May 5;15(7):1505–1513. doi: 10.1016/j.celrep.2016.04.038

Figure 2. Structure of Fab7968 in Complex with CFH Peptide.

Figure 2

(A) Fab 7968 shown with the heavy chain in green and the light chain in blue. The paratope with bound peptide in red is oriented toward the top of the figure, and the CDRs are marked and labeled.

(B) CFH peptide in its antibody-bound conformation (red) contrasted in a superposition to the same region in the natively folded CFH protein (gray). Here, only the 7968 epitope is highlighted in red (antibody-bound conformation) and yellow (on the natively folded protein). See also Figure S2 and Table S2.