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PDSinh-A01 increases ASL depth in IL-13-treated primary HBE cell cultures. A. Reconstructions of confocal z-stacks showing rhodamine dextran-labeled ASL in HBE and CFBE cells, without and with IL-13-treatment. PDSinh-A01 was used at 25 μM. B. Summary of ASL depth. Data shown as means ± sem (n = 6–12 cultures). *P < 0.05 compared to HBE cultures (no IL-13); **P < 0.05 compared to IL-13-treated cultures. IL-13 increased ASL depth for all conditions compared to no IL-13-treatment.
