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. 2016 May 19;7:724. doi: 10.3389/fmicb.2016.00724

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Copyright © 2016 Chen, Su, Wang, Zhang, Liu, Chen and Tan.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Expression levels of genes involved in antibiotic efflux and influx during tazobactam and gentamycin treatments. (A) Expression of efflux genes, (B) expression of influx genes. Expression levels of the genes were compared with those of WT (PCN033). 33-TZP/PCN033 indicates the expression levels in PCN033 during tazobactam treatment compared with those in untreated PCN033; K-TZP/PCN033 indicates the expression levels in the Δppk mutant during untreated PCN033.K-GEN/PCN033 indicates the expression levels in the Δppk mutant during gentamycin treatment compared with those in untreated PCN033.^***p < 0.000, ^**p < 0.01, ^*p < 0.05.