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. 2016 May 19;7:751. doi: 10.3389/fmicb.2016.00751

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Copyright © 2016 Zhang, He, Bi, Guo, Zhang, Wu, Liang, Yang, Tian, Ju, Fan, Chen, Guo and Luo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Differential gene expression profiles in the mouse brain tissue following CVS-11 and HEP-Flury infection at 10 dpi. (A) Graph showing the number and fold change of up-regulated and down-regulated genes (a threshold of ≥2-fold change in expression levels and adjusted P < 0.05) following virus infection. (B) A Venn diagram depicting the overlap of differentially expressed genes, and pie chart showing the number of genes that were up-regulated at different levels. (C) The representative GO terms of the common or unique, differentially regulated genes. (D) The representative KEGG pathways of the common or unique, differentially regulated genes. For more details, see the Supplementary Tables 2–9.