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. 2016 May 19;7:751. doi: 10.3389/fmicb.2016.00751

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Copyright © 2016 Zhang, He, Bi, Guo, Zhang, Wu, Liang, Yang, Tian, Ju, Fan, Chen, Guo and Luo.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Schematic overview of the differential expression of key genes involved in the immune responses to HEP-Flury and CVS-11 infection in the CNS. Genes, commonly up-regulated in HEP-Flury and CVS-11 infected brains are marked in red, uniquely up- and down-regulated in CVS-11 infected brains are marked in orange and green, respectively. Genes, up-regulated more significantly in response to the infection with HEP-Flury are marked in pink, uniquely up-regulated in HEP-Flury infected brains are marked in blue. +, indicates activation. −, indicates inhibition. Figure was produced using the elements of Servier Medical Art (http://www.servier.com/Powerpoint-image-bank).