Table 1.
Active Holistic Surveillance supplements.
| Supplement | Directions | Rationale | Citations |
|---|---|---|---|
| BroccoProtect | 3 capsules, daily | (i) Rich in glucosinolates and antioxidants (ii) Neutralizes the effect of heterocyclic amines found in meats (iii) Induces the apoptosis of prostate cancer cells and prohibits these cells from proliferating (iv) Protects somatic DNA from carcinogenic damage |
[6–8] |
|
| |||
| Omega 3 | 2000 mg, daily | (i) Suppresses inflammation (ii) Inhibits growth factor induced proliferation in prostate cancer cells |
[9, 10] |
|
| |||
| Zyflamend | 3 capsules, daily | (i) Suppresses inflammation (ii) Reduces growth of prostate cell lines (iii) Induces apoptosis of prostate cancer cells |
[11, 12] |
|
| |||
| Vitamin D3 | 5000 IU, daily | (i) Promotes differentiation of prostate cancer cells (ii) Induces apoptosis of prostate cancer cells (iii) Attenuates proliferation |
[13–15] |
|
| |||
| Genikinoko (GCP) | 1000 mg, twice daily | (i) Rich in genistein (ii) Causes cell cycle growth arrest (iii) Induces apoptosis of prostate cancer cells (iv) Antiangiogenesis properties in vitro and in vivo (v) Reduces serum PSA |
[6, 16–19] |
|
| |||
| Active Hexose Correlated Compound (AHCC) | 3 capsules, daily | (i) Boosts host immunity (ii) Protects against disorders induced by oxidative stress (iii) Reduces serum PSA |
[20–24] |
|
| |||
| Lycocell | 2 capsules, daily | (i) Lycopene complex (ii) Antioxidants protect DNA from damage (iii) Causes prostate cancer cell cycle arrest and apoptosis (iv) Induces differentiation (v) Reduces oxidative stress |
[25, 26] |