Table 2.
Metabolites | Plasma | Serum | CSF | Cortex | Hippocampus | Striatum | Thalamus | Midbrain | Whole brain tissue | Reference |
---|---|---|---|---|---|---|---|---|---|---|
Tyrosine | √ | √ | √ | [20, 22, 23] | ||||||
Serine | √ | √ | [50] | |||||||
Dopamine | √ | √ | √ | √ | √ | [20, 22, 23, 50, 51, 55] | ||||
Alanine | √ | √ | √ | √ | √ | [20, 22, 23, 27] | ||||
Citrulline | √ | √ | [23] | |||||||
Methionine | √ | [20] | ||||||||
γ-Aminobutyric acid (GABA) | √ | √ | √ | [23, 27, 28, 55] | ||||||
Threonine | √ | [50] | ||||||||
Glutamate | √ | √ | √ | √ | [21, 23, 27, 52, 55] | |||||
Valine | √ | √ | √ | [21, 50] | ||||||
Tryptophan | √ | √ | √ | [20, 23] | ||||||
Serotonin | √ | √ | √ | √ | √ | [51] | ||||
Glycine | √ | √ | √ | [22, 28, 50] | ||||||
Phenylalanine | √ | √ | √ | [21, 23] | ||||||
Glutamine | √ | √ | √ | [23, 27, 28, 55, 87] | ||||||
Glutamic acid | √ | √ | √ | [20–22, 50] | ||||||
Histidine | √ | √ | √ | [23] | ||||||
Aspartate | √ | √ | √ | √ | [20, 23, 27, 52] | |||||
Isoleucine | √ | √ | √ | [21] | ||||||
Leucine | √ | √ | [21] | |||||||
Nicotinuric acid | √ | √ | [27] | |||||||
Homocysteine | √ | [20] | ||||||||
Lysine | √ | [21] | ||||||||
Ornithine | √ | [50] | ||||||||
Arginine | √ | √ | [50] |