Figure 4.

Modality-specific regional signal change during episodic and semantic memory. A, Left, Percentage signal change for auditory (green), visual (purple), and audio-visual (blue) memories in the peak AnG voxel (−42, −66, 42) for the contrast “audio-visual − audio + visual” during episodic memory in the predefined spherical 6 mm ROI. Right, Left AnG activation for the same contrast. B, Left, Same as in A but for the peak AnG voxel (−42, −78, 36) for the main effect of audio-visual trials during semantic memory. Right, Left AnG activation for the same contrast. C, Overlay of activation maps shown in A and B. Red indicates activations selective to episodic memory, green indicates activations selective to semantic memory, and yellow indicates an overlap in activations. Activations are shown at a threshold of p < 0.05 (whole-brain, uncorrected) and are masked to the AAL mask for the ROI. The overlap shown in yellow comprised 1 voxel (−45, −72, 36) and did not reach significance in a conjunction analysis (t₍₁₅₎ = 1.85, p = 0.160). Note: Peak voxels were identified within the predefined spherical 6 mm ROIs using the contrasts specified above. Error bars indicate SEM. *p < 0.05, two-tailed t tests. Activations are shown at a threshold of p < 0.05 (whole-brain, uncorrected) and for the purposes of visualization are masked to the AAL mask for the ROI.