Table 1.
Baseline Demographic and Medical Characteristics by Endocrine Therapy Group
Characteristic | No. (%) of Patients | P* | |||
---|---|---|---|---|---|
Total (N = 186) | No Endocrine Therapy at T2 (n = 60) | Tamoxifen Initiated by T2 (n = 66) | Aromatase Inhibitor Initiated by T2 (n = 60) | ||
Mean (SD) age at T1, years | 52.0 (8.2) | 51.6 (8.6) | 46.9 (6.9) | 58.2 (3.8) | < .001 |
Mean (SD) months from diagnosis to T1 | 5.9 (2.6) | 6.0 (2.9) | 5.9 (2.4) | 5.8 (2.6) | .89 |
Mean (SD) months from last treatment to T1 | 1.2 (1.0) | 1.9 (1.1) | 1.0 (0.9) | 0.7 (0.6) | < .001 |
Ethnicity† | |||||
White, non-Hispanic | 148 (80) | 47 (78) | 48 (73) | 53 (88) | .09 |
Hispanic | 19 (10) | 5 (8) | 10 (15) | 4 (7) | |
Black | 5 (3) | 3 (5) | 2 (3) | 0 (0) | |
Asian | 8 (4) | 2 (3) | 5 (8) | 1 (2) | |
Other | 6 (3) | 3 (5) | 1 (2) | 2 (3) | |
Marital status | |||||
Married | 121 (65) | 40 (67) | 40 (61) | 41 (68) | .63 |
Not married | 65 (35) | 20 (33) | 26 (39) | 19 (32) | |
Education | |||||
Post college | 96 (52) | 30 (50) | 30 (45) | 36 (60) | .04 |
College | 55 (30) | 16 (27) | 28 (42) | 11 (18) | |
No college degree | 35 (19) | 14 (23) | 8 (11) | 13 (22) | |
Employment status | |||||
Full or part time | 122 (66) | 40 (67) | 44 (67) | 38 (63) | .90 |
Not employed | 64 (34) | 20 (33) | 22 (33) | 22 (37) | |
Annual household income, $ | |||||
≥ 100,000 | 110 (60) | 31 (52) | 45 (69) | 34 (58) | .15 |
< 100,000 | 73 (40) | 28 (47) | 20 (31) | 25 (42) | |
Surgery | |||||
Mastectomy | 63 (34) | 27 (45) | 23 (35) | 13 (22) | .03 |
Lumpectomy | 123 (66) | 33 (55) | 43 (65) | 47 (78) | |
Treatment | |||||
Chemotherapy and radiation | 74 (40) | 21 (35) | 23 (35) | 30 (50) | < .001 |
Chemotherapy only | 20 (11) | 4 (7) | 12 (18) | 4 (7) | |
Radiation only | 64 (34) | 16 (27) | 25 (38) | 23 (38) | |
Neither | 28 (15) | 19 (32) | 6 (9) | 3 (5) | |
Stage at diagnosis | |||||
0 | 25 (13) | 15 (25) | 9 (14) | 1 (2) | .02 |
I | 86 (46) | 22 (37) | 33 (50) | 31 (52) | |
II | 58 (31) | 17 (28) | 19 (29) | 22 (37) | |
III | 17 (9) | 6 (10) | 5 (8) | 6 (10) | |
Menstrual status at diagnosis and change | |||||
Postmenopausal before and after treatment | 100 (54) | 31 (52) | 13 (20) | 56 (93) | < .001 |
Premenopausal at diagnosis | 86 (46) | 29 (48) | 52 (80) | 4 (7) | |
Continued menstruating | 48 | 19 | 28 | 1 | |
Stopped menstruating | 37 | 10 | 24 | 3 | |
Missing data | 1 | 0 | 1 | 0 |
Abbreviations: SD, standard deviation; T1, baseline time point; T2, 6-month follow-up time point.
P values are from an analysis of variance for continuous variables and from the Pearson χ2 tests for categoric variables. P values ≤ .05 are statistically significant.
P value is for the comparison of white versus nonwhite ethnicities.