Table 2.
Patient Characteristics
Characteristic | Short-Term Maintenance (n = 82) | Long-Term Maintenance (n = 83) |
---|---|---|
Sex | ||
Female | 45 (55) | 57 (69) |
Male | 37 (45) | 26 (31) |
Median age, years (range) | 55 (34-81) | 57 (25-81) |
Disease status | ||
Untreated | 55 (67) | 58 (70) |
Relapsed/progressed | 27 (33) | 24 (29) |
Stable | 0 (0) | 1 (1) |
Previous chemotherapy | 20 (24) | 21 (25) |
Previous anti-CD20 | 9 (11) | 7 (8) |
Previous radiotherapy | 7 (9) | 5 (6) |
Grade | ||
1 and 2 | 69 (84) | 67 (81) |
3 | 5 (6) | 5 (6) |
3a | 5 (6) | 7 (9) |
3b | 0 (0) | 1 (1) |
Ann Arbor stage | ||
I and II | 19 (23) | 16 (19) |
III | 33 (40) | 29 (35) |
IV | 30 (37) | 37 (45) |
FLIPI risk | ||
Low | 26 (32) | 25 (31) |
Intermediate | 35 (43) | 29 (36) |
High | 20 (25) | 27 (33) |
Elevated LDH | 6 (7) | 19 (23) |
Nodal areas ≥ 4 | 45 (55) | 49 (60) |
Extranodal sites | 18 (22) | 37 (45) |
Bulky disease > 5 cm | 22 (27) | 23 (28) |
B symptoms | 14 (17) | 12 (14) |
Fever > 38°C | 5 (6) | 2 (2) |
Drenching sweats | 11 (13) | 10 (12) |
Weight loss | 4 (5) | 2 (2) |
NOTE. Data are given as No. (%) unless otherwise noted.
Abbreviations: FLIPI, Follicular Lymphoma International Prognostic Index; LDH, lactate dehydrogenase.