Table 1.

Patient Characteristics

Patient No.	Age (Years)	Sex	Type of Transplant	Malignancy	Malignancy Status Immediately Before CAR T-Cell Infusion	Blood B-Lymphocyte Count Immediately Before CAR T-Cell Infusion (Cells/μL)*	Blood NK-Cell Count Immediately Before CAR T-Cell Infusion (Cells/μL)†	Blood T-Cell Count Immediately Before CAR T-Cell Infusion (Cells/μL)‡
1	66	M	URD 10/10 HLA match	CLL	PD	286	81	3,873
2	44	M	Sibling	DLBCL	PD	7	53	394
3	55	M	Sibling	CLL	SD	4	42	1,954
4	49	M	Sibling	DLBCL	SD	0	177	323
5	44	F	URD 10/10 HLA match	CLL	PD	319	192	3,362
6	48	M	Sibling	MCL	SD	1	97	1,176
7	48	M	URD 10/10 HLA match	CLL	PD	1,805	164	1,981
8	63	F	Sibling	MCL	PR	1	86	354
9	57	M	URD 10/10 HLA match	MCL	SD	0	169	479
10	50	M	Sibling	MCL	PD	83	101	712
11	59	F	URD 9/10 HLA match	CLL	PD	3,372	275	1,216
12	68	F	Sibling	ALL Ph+	Relapse	0	38	184
13	61	F	Sibling	MCL	PR	1	133	2,024
14	32	M	Sibling	ALL Ph-neg	PD	1	148	370
15	20	F	Sibling	ALL Ph-neg	PD	127	79	867
16	25	F	Sibling	ALL Ph-neg	PD	0	15	291
17	46	F	Sibling	DLBCL	PD	2	26	2,171
18	54	M	Sibling	DLBCL	PD	325	209	809
19	47	F	URD 10/10 HLA match	FL transformed to DLBCL	PD	0	64	22
20	25	M	URD 9/10 HLA match	ALL Ph-neg	Relapse	1,109	269	1,766

Abbreviations: ALL Ph+, Philadelphia chromosome-positive acute lymphoblastic leukemia; ALL Ph-neg, Philadelphia chromosome-negative acute lymphoblastic leukemia; CAR, chimeric antigen receptor; CLL, chronic lymphocytic leukemia; DLBCL, diffuse large–B-cell lymphoma; FL, follicular lymphoma; MCL, mantle cell lymphoma; NK, natural killer; PD, progressive disease; PR, partial remission; SD, stable disease; Sibling, HLA-matched sibling donor; URD, unrelated donor.

^*Normal range of blood B-lymphocyte (CD19⁺) count is 81 to 493/μL.

^†Normal range of blood NK cells (CD3⁻, CD56⁺) is 109 to 607/μL.

^‡Normal range of blood T (CD3⁺) cells is 615 to 2,348/μL.