Table 1.
Summary of Clinicopathologic Factors Stratified by Lymphedema (RVC/WAC ≥ 10%)
| Lymphedema | Overall (N = 760) | ||
|---|---|---|---|
| No (n = 697) | Yes (n = 63) | ||
| Age at diagnosis, years* | 52 | 51 | 52 |
| BMI, lb/in2* | 25.4 | 29.1 | 25.6 |
| Follow-up, months* | 23.59 | 34.31 | 24.03 |
| No. of postoperative visits* | 4 | 5 | 4 |
| Months between visits* | 7.14 | 6.45 | 7.09 |
| Tumor type | |||
| None | |||
| No. | 112 | 13 | 125 |
| % | 16.1 | 20.6 | 16.4 |
| Invasive | |||
| No. | 583 | 50 | 633 |
| % | 83.6 | 79.4 | 83.3 |
| Not available | |||
| No. | 2 | 0 | 2 |
| % | 0.3 | 0 | 0.3 |
| Laterality | |||
| Unilateral | |||
| No. | 473 | 31 | 504 |
| % | 67.9 | 49.2 | 66.3 |
| Bilateral | |||
| No. | 224 | 32 | 256 |
| % | 32.1 | 50.8 | 33.7 |
| Breast surgery | |||
| Lumpectomy | |||
| No. | 359 | 18 | 377 |
| % | 51.5 | 28.6 | 49.6 |
| Mastectomy | |||
| No. | 338 | 45 | 383 |
| % | 48.5 | 71.4 | 50.4 |
| Axillary surgery | |||
| None | |||
| No. | 53 | 7 | 60 |
| % | 7.6 | 11.1 | 7.9 |
| SLNB | |||
| No. | 519 | 22 | 541 |
| % | 74.5 | 34.9 | 71.2 |
| ALND | |||
| No. | 125 | 34 | 159 |
| % | 17.9 | 54 | 20.9 |
| Neoadjuvant chemotherapy | |||
| No | |||
| No. | 606 | 50 | 656 |
| % | 86.9 | 79.4 | 86.3 |
| Yes | |||
| No. | 91 | 13 | 104 |
| % | 13.1 | 20.6 | 13.7 |
| Adjuvant chemotherapy | |||
| No | |||
| No. | 416 | 25 | 441 |
| % | 59.7 | 39.7 | 58 |
| Yes | |||
| No. | 281 | 38 | 319 |
| % | 40.3 | 60.3 | 42 |
| Hormonal therapy | |||
| No | |||
| No. | 121 | 12 | 133 |
| % | 17.4 | 19 | 17.5 |
| Yes | |||
| No. | 576 | 51 | 627 |
| % | 82.6 | 81 | 82.5 |
| Radiation therapy | |||
| None | |||
| No. | 248 | 17 | 265 |
| % | 35.6 | 27 | 34.9 |
| Chest wall only | |||
| No. | 316 | 16 | 332 |
| % | 45.3 | 25.4 | 43.7 |
| RLNR | |||
| No. | 130 | 30 | 160 |
| % | 18.7 | 47.6 | 21.1 |
| Not available | |||
| No. | 3 | 0 | 3 |
| % | 0.4 | 0 | 0.4 |
| Cellulitis | |||
| No | |||
| No. | 659 | 56 | 715 |
| % | 94.5 | 88.9 | 94.1 |
| Yes | |||
| No. | 38 | 7 | 45 |
| % | 5.5 | 11.1 | 5.9 |
Abbreviations: ALND, axillary lymph node dissection; BMI, body mass index; RNLR, regional lymph node irradiation; RVC, relative volume change; SLNB, sentinel lymph node biopsy; WAC, weight-adjusted volume change.
*
Values shown, median.