Table 2.

Patient Characteristics and Outcome

Patient Cohort	No. (%)	3-Year EFS ± SE (%)	P (EFS Log-Rank)	3-Year OS ± SE (%)	P (OS Log-Rank)
Overall	229	44.4 ± 4.3	N/A	58.2 ± 4.4	N/A
Age at diagnosis, months
< 18	42 (18)	53.1 ± 9.7	.284	60.7 ± 9.8	.943
≥ 18	187 (82)	42.4 ± 4.7		57.6 ± 4.9
INSS stage
Non–stage 4	40 (17)	67.0 ± 9.9	.002	76.4 ± 9.0	.023
Stage 4	189 (83)	39.4 ± 4.6		54.0 ± 4.9
MYCN status
Nonamplified	105 (48)	52.4 ± 7.0	.006	70.5 ± 6.5	< .001
Amplified	112 (52)	37.0 ± 5.4		45.7 ± 5.8
Histology
Favorable	18 (13)	81.3 ± 12.4	.035	80.8 ± 12.5	.133
Unfavorable	107 (87)	48.9 ± 6.3		60.1 ± 6.5

Abbreviations: EFS, event-free survival; INSS, International Neuroblastoma Staging System; N/A, not applicable; OS, overall survival.