Table 2.

Mean Quality-of-Life Changes From Baseline at 6 Months

Patients	N*	STAR (n = 277)	Usual Care (n = 180)	P (Univariable)†	P (Multivariable)†	Effect Size
Evaluable patients*	457
EQ-5D at baseline		86.2 (84.7 to 87.7)	86.6 (84.7 to 88.5)
EQ-5D at 6 months		84.8 (83.2 to 86.4)	79.5 (76.7 to 82.2)
Point drop from baseline		1.4 (0.4 to 3.1)	7.1 (4.8 to 9.5)
Difference in point drop between arms		5.7		<.001	<.001	0.37
Subgroup analysis
Computer-inexperienced subgroup*	116
EQ-5D at baseline		83.6 (80.2 to 86.9)	86.9 (81.9 to 91.9)
EQ-5D at 6 months		81.8 (78.2 to 85.3)	78.6 (71.2 to 86.0)
Point drop from baseline		1.8 ( to 2.1 to 5.7)	8.3 (3.6 to 13.1)
Difference in point drop between arms		6.5		.06	.11	0.38
Computer-experienced subgroup*	341
EQ-5D at baseline		87.3 (85.7 to 88.6)	86.5 (84.5 to 88.6)
EQ-5D at 6 months		86.1 (84.3 to 87.8)	79.7 (76.7 to 82.7)
Point drop from baseline		1.2 (0.7 to 3.1)	6.9 (4.2 to 9.5)
Difference in point drop between arms		5.7		<.001	<.001	0.38

NOTE. Data presented as mean (95% CI) unless otherwise noted.

Abbreviations: STAR, Symptom Tracking and Reporting web-based self-reporting system; EQ-5D, EuroQoL EQ-5D quality of life questionnaire.

^*Patents without postbaseline EQ-5D scores were not included in the primary health-related quality of life analysis but were included in the sensitivity analysis with similar results.

^†P values for between-arm comparisons. Multivariable analyses controlled for age, sex, cancer type, race, and education level. For overall analyses, subgroup assignment (computer experienced or computer inexperienced) was also included as a covariate.