Table 2.
Outcome Probabilities Stratified by Disease Status
| Outcome | Patients in MRD-Negative Remission (n = 235) | Patients in MRD-Positive Remission (n = 76) | Patients With Active AML (n = 48) |
|---|---|---|---|
| OS at 3 years | 73 (66-78) | 26 (17-37) | 23 (12-35) |
| PFS at 3 years | 67 (61-73) | 12 (5-21) | 13 (5-23) |
| Cumulative incidence of relapse at 3 years | 22 (16-28) | 67 (55-77) | 65 (49-76) |
| Cumulative incidence of NRM at 3 years | 11 (7-15) | 21 (13-31) | 23 (12-35) |
| Grade 3or 4 acute GVHD at 100 days | 8 (5-12) | 17 (10-27) | 15 (7-27) |
| Chronic GVHD at 18 months | 60 (49-71) | 61 (54-67) | 54 (40-68) |
NOTE. All data are given as percent (range).
Abbreviations: GVHD, graft-versus-host disease; MRD, minimal residual disease; neg, negative; NRM, nonrelapse mortality; OS, overall survival; PFS, progression-free survival; pos, positive.