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Molecular signatures and functional subtypes of human ex vivo generated monocyte-derived macrophages. LPS and IFN-γ are grouped as M1-driving stimuli. IL-4, dexamethasone (Dex) and TGF-β are grouped as M2-driving stimuli. The list of specifically activated genes is indicated for each macrophage subtype. The most pronounced functional activities for each macrophage subtype are defined according to the molecular profile and functional tests.
