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. 2016 Feb 11;44(9):4189–4199. doi: 10.1093/nar/gkw087

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© The Author(s) 2016. Published by Oxford University Press on behalf of Nucleic Acids Research.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com

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Figure 2. — The effect of inhibitors on DNA pairing activity of RAD52. (A) The products of DNA pairing (D-loops) were analyzed by electrophoresis in 1% agarose gels. (B) Graphical representation of the data from A. (C) The IC₅₀ values for 17 tested compounds. (D) The effect of the RAD52 inhibitors on DNA pairing activity of RAD51. The effect was measured using the D-loop assay at the inhibitors concentrations that correspond to their 10 x IC₅₀ values (27–176 μM) for RAD52 pairing activity; concentrations of A05 and B02 were 100 μM. Error bars indicate SD.