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. 2016 Apr 16;44(9):3971–3988. doi: 10.1093/nar/gkw237

Figure 7.

Figure 7.

The slow kinetics of unconventional DNA intercalation, from (45). (A) Stretch-release cycles of the DNA–ActD complex show considerable hysteresis between the stretch (solid lines) and release (dashed lines) parts of the cycle, indicating non-equilibrium measurements. (B) Measurements illustrating the slow kinetics of unconventional DNA intercalation and showing how constant force measurements ensure that DNA equilibrium elongation is reached.