Alcohol users only, cannabis users only, and both alcohol and cannabis users shown as a proportion of all users of any substance at each of waves 1 to 8, by 3 levels of use: any, moderate risk, and high risk. The x-axis scale reflects the relative timing of each survey. At least moderate use alcohol was defined as follows: in the week prior to survey, exceeded 28 standard drinks (SD) (1 SD = 10 g of alcohol) in males and 14 SDs in females. High-risk drinking was defined as follows: exceeded 43 SDs in males and 28 SDs in females. At least moderate risk cannabis use was defined as currently using at least weekly and high-risk use as currently using daily for both males and females. Figure from Patton et al.24