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The uptake of BGC-823 cells with fluorescein isothiocyanate (FITC)-labeled (A) anti-epidermal growth factor receptor-diethylene triamine penta-acetate-gadolinium (anti-EGFR-DTPA-Gd) and (B) anti-EGFR-internalizing arginine-glycine-aspartic acid (iRGD)-DTPA-Gd was analyzed. BGC-823 cells were incubated with a sub-saturating concentration of (A) anti-EGFR-DTPA-Gd and (B) anti-EGFR-iRGD-DTPA-Gd. Nuclei were stained with Hoechst 33258. Fuorescence images are shown (magnification, x200).
