Table 3.

Pearson Correlations Between Selected MPN-SAF TSS Items and Alternative Measures of MPN Disease Burden (n = 1,408)

Item	Measurement Instrument	Associated Measure	Pearson Correlation*
Worst fatigue (1-item BFI)	QLQ-C30 Symptom Scale	Fatigue	0.66
	Overall QOL	Overall QOL	0.53
	Physicians' perceptions	Fatigue	0.51
Inactivity	QLQ-C30 Functional Scale	Physical	0.58
		Role	0.60
		Social	0.52
	QLQ-C30 Symptom Scale	Fatigue	0.59
Concentration	QLQ-C30 Functional Scale	Cognitive	0.63
	QLQ-C30 Symptom Scale	Fatigue	0.52
	Overall QOL	Overall QOL	0.53
Itching	Physicians' perceptions	Itching	0.54
Bone pain	QLQ-C30 Symptom Scale	Pain	0.53
Weight loss	Physicians' perceptions	Weight loss	0.54
MPN-SAF TSS†	QLQ-C30 Functional Scale	Physical	0.57
		Role	0.51
		Emotional	0.51
		Global health/QOL	0.51
	QLQ-C30 Symptom Scale	Fatigue	0.65
		Pain	0.56
	Physicians' perceptions	Average physician's perception	0.51
	Overall QOL	Overall QOL	0.59

Abbreviations: BFI, Brief Fatigue Inventory; MPN, myeloproliferative neoplasm; MPN-SAF TSS, Myeloproliferative Neoplasm Symptom Assessment Form total symptom score; QLQ-C30, [European Organisation for Research and Treatment of Cancer] Quality of Life Questionnaire C30; QOL, quality of life.

^*For all items, P < .001. Absolute value of Pearson correlation is reported.

^†MPN-SAF TSS is the average score of worst fatigue, concentration, early satiety, inactivity, night sweats, itching, bone pain, abdominal discomfort, weight loss, and fever.