Table 3.
Clinical outcome of 93 cases of bone and joint infection due to Streptococcus species
| Characteristic | Value |
|---|---|
| Remission at 1 year after end of treatment | 76 (82) |
| Death | 7 (8) |
| During treatment period | 4 (4) |
| After end of treatment | 3 (3) |
| Causes of death | |
| Death by infection | 1 (1) |
| Death by cancer | 3 (3) |
| Death by acute respiratory distress syndrome caused by severe pneumonia | 2 (2) |
| Death by suicide | 1 (1) |
| Unfavourable clinical outcomes | 16 (17) |
| Death by infection | 1 (1) |
| Failure during treatment | 8 (9) |
| Median time to failure | 141 days |
| Evolution | |
| Remission after further ATB | 1 (1) |
| Failure after further treatment | 4 (4) |
| Wound care only | 2 (2) |
| Wound care with suppressive antibiotic therapy | 2 (2) |
| Remission after osteosynthesis removal and antibiotic therapy | 1 (1) |
| Amputation | 2 (2) |
| Relapse | 7 (8) |
| Median time to relapse (after end of treatment) | 218 days |
| Evolution (after further treatment) | |
| Remission | 2 (2) |
| Amputation | 5 (5) |
| Amputation | 19 (20) |
| Median time to amputation (from date of infection) | 447 days |
| Type of infection | |
| Diabetic foot | 11 (12) |
| Ischemic foot | 1 (1) |
| Chronic wound of foot | 1 (1) |
| Chronic osteitis | 5 (5) |
| Joint prosthesis infection | 1 (1) |
| Delay of amputation | |
| Before starting antibiotic treatmenta | 3 (3) |
| Diabetic foot | 3 (3) |
| During antibiotic treatment | 10 (11) |
| Neoplastic transformation | 1 (1) |
| Ischemic foot | 1 (1) |
| Diabetic foot | 5 (5) |
| Chronic osteitis | 2 (2) |
| Joint prosthesis infection | 1 (1) |
| Treatment failure | 0 |
| After end of antibiotic treatmenta | 7 (8) |
| Neoplastic transformation | 0 |
| Ischemic foot | 0 |
| Diabetic foot | 4 (4) |
| Chronic osteitis | 3 (3) |
| Joint prosthesis infection | 0 |
| Failure to treatment | 2 (2) |
| Relapse | 5 (5) |
| Reason for amputation | |
| Treatment failure | 2 (2) |
| Relapse | 6 (6) |
| Other | 11 (12) |
| Neoplastic transformation of foot osteitis | 1 (1) |
| Ischemic foot | 1 (1) |
| Diabetic foot | 6 (6) |
| Chronic osteitis | 2 (2) |
| Joint prosthesis infection | 1 (1) |
Data are presented as n (%) unless otherwise indicated.
a
Unfavourable clinical outcome was included in cases of treatment failure and relapse.