Table 4.
Summary of Patients With Acute Renal Failure
| Age (years) | Sex | Baseline Creatinine (mg/dL) | Onset | Dose (mg/m2) | Associated Event | Other Possible Nephrotoxics |
|---|---|---|---|---|---|---|
| 58 | Male | 1.7 | Course 2 day 6 | 20* | Fungal pneumonia, sepsis (E. faecium) | Liposomal amphotericin B |
| 70 | Male | 1.8 | Course 2 day 8 | 20† | Sepsis (K. pneumoniae), pneumonia | Levofloxacin |
| 72 | Male | 1.8 | Course 1 day 31 | 30 | Pneumonia, sepsis, tumor lysis syndrome | Moxifloxacin |
| 54 | Female | 0.8 | Course 1 day 10 | 30 | Pneumonia, sepsis (E. faecalis), supraventricular arrhythmia | Vancomycin, amikacin |
NOTE. All four patients required renal replacement therapy.
Reduced from 40 mg/m2 starting dose.
Reduced from 30 mg/m2 starting dose.