Table 2.
Percent Change in Estrogen Levels From Baseline to Each Time Point Among Patients Randomly Assigned to Exemestane Plus Triptorelin
| Estrogen Level | Percentage of Change From Baseline | ||
|---|---|---|---|
| 3 Months | 6 Months | 12 Months | |
| No. of patients* | 64 | 66 | 63 |
| Estradiol, pg/mL | |||
| Mean (SD) | −76 (76) | −82 (62) | −85 (46) |
| Geometric mean | −88 | −90 | −83 |
| Median (IQR) | −96 (−99 to −83) | −96 (−99 to −85) | −97 (−99 to −87) |
| Estrone, pg/mL | |||
| Mean (SD) | −90 (18) | −87 (27) | −82 (61) |
| Geometric mean | −78 | −79 | −91 |
| Median (IQR) | −95 (−98 to −91) | −95 (−98 to −91) | −95 (−98 to −90) |
| Estrone sulfate, pg/mL | |||
| Mean (SD) | −89 (27) | −86 (36) | −93 (13) |
| Geometric mean | −90 | −89 | −92 |
| Median (IQR) | −98 (−99 to −93) | −97 (−99 to −92) | −98 (−99 to −94) |
Abbreviations: IQR, interquartile range; SD, standard deviation;.
*
Denotes the number of patients with two samples, at baseline and at specified time point, to calculate change.