Table A5.

HRs Comparing OM Between Non-RT Group and RT Group According to Clinicopathologic Factors

Subgroup	No. of Patients		Weighted 10-Year OM Rate (%)		Weighted Multivariable* HR	95% CI*	P*
	Non-RT Group	RT Group	Non-RT Group	RT Group
Age, years
< 40	329	567	4.5	1.8	0.30	0.12 to 0.74	.009
40-60	5,545	11,697	4.6	3.7	0.68	0.58 to 0.80	< .001
> 60	5,941	8,065	26.6	23.1	0.78	0.73 to 0.84	< .001
Tumor size, mm
< 16	9,493	15,255	13.5	12.0	0.81	0.74 to 0.87	.05
16-40	1,919	4,484	16.4	12.1	0.64	0.56 to 0.74	< .001
> 40	403	590	18.2	18.0	0.58	0.41 to 0.82	.003
Grade
1	2,626	2,549	14.4	13.8	1.01	0.93 to 1.27	.29
2	5,594	7,923	14.4	12.6	0.79	0.71 to 0.88	< .001
3	3,595	9,857	14.0	11.1	0.66	0.59 to 0.73	< .001
Total patients	11,815	20,329	14.2	12.2	0.76	0.71 to 0.81	< .001

Abbreviations: HR, hazard ratio; OM, overall mortality; RT, radiotherapy.

^*Multivariable analysis adjusted by age of patients, year of diagnosis, race, tumor size, nuclear grade, and marital status.